Junxiang Wan Selected Research

humanin

1/2022	Effect of Humanin G (HNG) on inflammation in age-related macular degeneration (AMD).
1/2020	The mitochondrial derived peptide humanin is a regulator of lifespan and healthspan.
11/2018	Chronic treatment with the mitochondrial peptide humanin prevents age-related myocardial fibrosis in mice.
1/2018	Humanin Prevents Age-Related Cognitive Decline in Mice and is Associated with Improved Cognitive Age in Humans.
11/2017	Mitochondrially derived peptides as novel regulators of metabolism.
3/2016	The Mitochondrial-Derived Peptide Humanin Protects RPE Cells From Oxidative Stress, Senescence, and Mitochondrial Dysfunction.
12/2015	The Potent Humanin Analogue (HNG) Protects Germ Cells and Leucocytes While Enhancing Chemotherapy-Induced Suppression of Cancer Metastases in Male Mice.
4/2015	The effect of sex on humanin levels in healthy adults and patients with uncomplicated type 1 diabetes mellitus.
11/2011	Humanin preserves endothelial function and prevents atherosclerotic plaque progression in hypercholesterolemic ApoE deficient mice.

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Junxiang Wan Research Topics

Disease

10	Poisoning 05/2010 - 10/2002
8	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 08/2011
7	Neoplasms (Cancer) 01/2019 - 08/2011
5	Insulin Resistance 01/2021 - 03/2015
3	Inflammation (Inflammations) 01/2022 - 01/2007
3	Breast Neoplasms (Breast Cancer) 12/2021 - 01/2021
3	Cognitive Dysfunction 01/2018 - 04/2013
2	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 04/2013
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2019 - 03/2016
2	Neoplasm Metastasis (Metastasis) 12/2015 - 08/2011
2	Obesity 03/2015 - 05/2013
1	Macular Degeneration (Age-Related Maculopathy) 01/2022
1	Atrophy 01/2021
1	Sarcopenia 01/2021
1	Muscular Atrophy (Muscle Atrophy) 01/2021
1	Stroke (Strokes) 01/2020
1	Lactic Acidosis 01/2020
1	MELAS Syndrome (Syndrome, MELAS) 01/2020
1	Mitochondrial encephalopathy 01/2020
1	Fibrosis (Cirrhosis) 11/2018
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2018
1	Weight Gain 11/2017
1	Retinal Degeneration 03/2016
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 04/2015
1	Melanoma (Melanoma, Malignant) 03/2014
1	Overweight 05/2013
1	Atherosclerotic Plaque (Atheroma) 11/2011
1	Atherosclerosis 11/2011
1	Genomic Instability 10/2009
1	Allergic Rhinitis 01/2007
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2007
1	Asthma (Bronchial Asthma) 01/2007

Drug/Important Bio-Agent (IBA)

12	Peptides (Polypeptides)IBA 01/2022 - 11/2011
10	Benzene (Benzole)IBA 05/2010 - 10/2002
9	humaninIBA 01/2022 - 11/2011
7	Insulin-Like Growth Factor I (IGF-1)IBA 02/2016 - 12/2011
5	Proteins (Proteins, Gene)FDA Link 01/2022 - 08/2011
4	Biomarkers (Surrogate Marker)IBA 12/2021 - 12/2011
4	Insulin (Novolin)FDA Link 11/2017 - 07/2012
3	EnzymesIBA 12/2021 - 12/2002
3	Insulin-Like Growth Factor Binding Protein 1IBA 05/2013 - 12/2011
2	Mitochondrial DNA (mtDNA)IBA 01/2022 - 11/2017
2	Glucose (Dextrose)FDA LinkGeneric 11/2017 - 05/2013
2	IGF Type 1 Receptor (IGF 1 Receptor)IBA 07/2013 - 07/2012
2	ganitumabIBA 07/2013 - 07/2012
2	Dietary Fats (Dietary Fat)IBA 07/2012 - 12/2011
2	Environmental Pollutants (Pollutants, Environmental)IBA 01/2007 - 01/2007
2	Vehicle Emissions (Emissions, Vehicle)IBA 01/2007 - 01/2007
1	Interleukin-17 (Interleukin 17)IBA 01/2022
1	E-SelectinIBA 01/2022
1	P-SelectinIBA 01/2022
1	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2022
1	Interleukin-13IBA 01/2022
1	Semaphorins (Semaphorin)IBA 12/2021
1	ImmunosorbentsIBA 12/2021
1	Palmitic Acid (Hexadecanoic Acid)IBA 01/2021
1	MyostatinIBA 01/2021
1	GlucocorticoidsIBA 01/2019
1	Glycogen Synthase KinasesIBA 11/2018
1	Peptide Hormones (Polypeptide Hormones)IBA 11/2017
1	Gly(14)-HumaninIBA 12/2015
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 12/2015
1	12S ribosomal RNAIBA 03/2015
1	AndrogensIBA 05/2013
1	cixutumumabIBA 05/2013
1	Insulin-Like PeptidesIBA 05/2013
1	Monoclonal AntibodiesIBA 05/2013
1	Amino Acids FDA Link 04/2013
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 07/2012
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 12/2011
1	Fish OilsIBA 12/2011
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 12/2011
1	CholesterolIBA 11/2011
1	Apolipoproteins E (ApoE)IBA 11/2011
1	Insulin-Like Growth Factor Binding Protein 3IBA 08/2011
1	Insulin-Like Growth Factor Binding ProteinsIBA 08/2011
1	Tumor Suppressor Protein p14ARF (p14ARF)IBA 10/2009
1	Messenger RNA (mRNA)IBA 06/2009
1	Codon (Codons)IBA 12/2008
1	DNA (Deoxyribonucleic Acid)IBA 12/2008
1	ADP Ribose Transferases (ADP Ribosyltransferase)IBA 11/2005
1	Glutathione Transferase (Glutathione S-Transferase)IBA 12/2002
1	Peroxidase (Myeloperoxidase)IBA 12/2002
1	Cytochrome P-450 CYP2E1 (CYP2E1)IBA 12/2002
1	NAD (NADH)IBA 12/2002
1	quinone (benzoquinone)IBA 12/2002
1	NucleotidesIBA 12/2002
1	Oxidoreductases (Dehydrogenase)IBA 12/2002
1	1- nitro- 9- (5- dimethylaminopentylamino)anthracene dihydrochlorideIBA 12/2002
1	Complementary DNA (cDNA)IBA 12/2002

Therapy/Procedure

5	Therapeutics 01/2021 - 07/2012
2	Fat-Restricted Diet (Diet, Fat Restricted) 07/2012 - 12/2011
1	Modified Radical Mastectomy (Mastectomy, Modified) 12/2021
1	Drug Therapy (Chemotherapy) 12/2015
1	Caloric Restriction 12/2015
1	Protein-Restricted Diet (Diet, Protein Restricted) 03/2014
1	Prostatectomy (Retropubic Prostatectomy) 05/2013